Neonatal enteropathies: defining the causes of protracted diarrhea of infancy.
نویسندگان
چکیده
The underlying causes of chronic diarrhea beginning early in life are increasingly well defined. Infectious and post-infectious enteropathies and food sensitive/allergic enteropathy account for the majority of cases. Recent attention has focused on characterizing defined entities, which cause protracted diarrhea in infants and young children. Disorders of intestinal ion transport usually present at birth following a pregnancy complicated by polyhydramnios. Intestinal mucosal biopsies show normal architect with intact villus-crypt axis. Neonatal enteropathies, by contrast, are characterized by blunting of the villi. These include microvillus inclusion disease, tufting enteropathy, autoimmune enteropathy and IPEX syndrome - and it is these conditions that are the subject of the current review.
منابع مشابه
Immune and Autoimmune Enteropathies
Autoimmune enteropathy characteristically presents in infancy with protracted diarrhea. Underlying disorders of immune function, including regulatory T cells, must be excluded. Treatment options include nutritional rehabilitation, immune suppression, and, in select cases, bone marrow transplant. Copyright © 2006 Nestec Ltd., Vevey/S. Karger AG, Basel
متن کاملEnteropathies of Infancy
INTRODUCTION Acute diarrhea, in the industrialized world, is usually self-limited, infectious in nature, and rarely requires biopsy evaluation. Chronic diarrhea can cause failure to thrive, frequently results in intestinal biopsy and may require parenteral nutrition and other forms of therapy. Protracted diarrhea has replaced the older term “intractable diarrhea” in the GI literature and denote...
متن کاملAssessment of chronic diarrhea in early infancy in Tehran Tertiary Care Center; Tehran-Iran
Introduction Chronic diarrhea of infancy is a heterogeneous syndrome that includes several diseases with different etiologies. The aim of this study was investigating chronic diarrhea, its etiologies, clinical features and outcomes in infancy.Materials and Methods Retrospective study investigating infants hospitalized in the gastroenterology department of Tehran tertiary care center.The main de...
متن کاملThe prevalence of coronavirus in fecal samples of neonatal calf diarrhea using electron microscopic examination
BACKGROUND:Neonatal calf diarrhea (NCD), also known ascalf scours, is caused by viruses, bacteria, and parasites.Coronavirus is one of the important causes of NCD syndrome.Electron microcopy has been used for demonstration of virusesin fecal samples of diarrheic calves since 1969. OBJECTIVES:The aim of this study was to determine the prevalence ofcoronavirus in fecal samples of neonatal calf di...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of pediatric gastroenterology and nutrition
دوره 38 1 شماره
صفحات -
تاریخ انتشار 2004